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Hallucinogens
Hallucinogens are
among the oldest known group of drugs used for their ability to alter
human perception and mood. For centuries, many of the naturally occurring
hallucinogens found in plants and fungi have been used for a variety of
shamanistic practices. In more recent years, a number of synthetic hallucinogens
have been produced, some of which are much more potent than their naturally
occurring counterparts.
The biochemical,
pharmacological, and physiological basis for hallucinogenic activity is
not well understood. Even the name for this class of drugs is not ideal,
since hallucinogens do not always produce hallucinations.
However, taken in
non-toxic dosages, these substances produce changes in perception, thought,
and mood. Physiological effects include elevated heart rate, increased
blood pressure, and dilated pupils. Sensory effects include perceptual
distortions that vary with dose, setting, and mood. Psychic effects include
disorders of thought associated with time and space. Time may appear to
stand still and forms and colors seem to change and take on new significance.
This experience may be either pleasurable or extremely frightening. It
needs to be stressed that the effects of hallucinogens are unpredictable
each time they are used.
Weeks or even months
after some hallucinogens have been taken, the user may experience flashbacks--fragmentary
recurrences of certain aspects of the drug experience in the absence of
actually taking the drug. The occurrence of a flashback is unpredictable,
but is more likely to occur during times of stress and seem to occur more
frequently in younger individuals. With time, these episodes diminish
and become less intense.
The abuse of hallucinogens
in the United States received much public attention in the 1960s and 1970s.
A subsequent decline in their use in the 1980s may be attributed to real
or perceived hazards associated with taking these drugs. However, a resurgence
of the use of hallucinogens in the 1990s is cause for concern. By 1999,
one out of every six college students (14.8 percent) reported some use
of hallucinogens in their lifetime, and an estimated 900,000 Americans
12 years of age or older, were current users of hallucinogens. Hallucinogenic
mushrooms, LSD, and MDMA are popular among junior and senior high school
students who use hallucinogens.
There is a considerable
body of literature that links the use of some of the hallucinogenic substances
to neuronal damage in animals, and recent data support that some hallucinogens
are neurotoxic to humans. However, the most common danger of hallucinogen
use is impaired judgment that often leads to rash decisions and accidents.
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